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KMID : 1177320200230010001
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Korean Journal of Schizophrenia Research
2020 Volume.23 No. 1 p.1 ~ p.7
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Factors Affecting the Duration of Untreated Psychosis in Community-Dwelling Patients with Schizophrenia Spectrum Disorder
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Kim Mi-Na
Kim Jae-Kyeong
Jhon Min
Kim Ju-Wan
Lee Ju-Yeon
Kim Jae-Min
Shin Il-Seon
Yoon Jin-Sang
Lee Myung-Soo
Kim Sung-Wan
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Abstract
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Objectives: This study aimed to identify factors affecting the duration of untreated psychosis (DUP) in patients with schizophrenia spectrum disorder.
Methods: Six-hundred patients with schizophrenia spectrum disorder were recruited from mental health welfare centers in Gwangju Metropolitan City and Gyeonggi-do. Subjects were categorized into two groups according to median DUP. Demographic and clinical characteristics were compared between the two groups.
Results: The mean DUP was 80.8 weeks, and the median DUP was 15.9 weeks. Patients with Medicaid, higher age, and longer duration of the schizophrenia prodrome were more likely to have a longer DUP. The DUP was shorter in patients who were consulted by family/relatives prior to treatment. Patients visiting university hospitals were more likely to have a shorter DUP compared with those visiting psychiatric clinics or small-sized mental hospitals, i.e., with less than 100 beds. A multivariate regression analysis showed that the duration of the prodrome was a factor that significantly affected DUP.
Conclusion: The vulnerable group of patients with schizophrenia with a long DUP should be monitored closely. Moreover, it is necessary to develop a strategy to identify patients who have an insidious course of psychosis to reduce the DUP.
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KEYWORD
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Community, Duration of untreated psychosis (DUP), Early intervention, Psychosis, Schizophrenia
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